Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys

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Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys

BACKGROUND Being one of the most common nasal diseases, chronic rhinosinusitis (CRS) is subdivided into CRS with nasal polyps (NP) and CRS without nasal polyps (CRSsNP). CRSsNP presents itself with a TH1 milieu and neutrophil infiltration, while NP is characterised by a mixed TH1/TH2 profile and an influx of predominantly eosinophils, plasma cells and mast cells. For the purpose of discovering ...

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Comparison of Sinonasal Symptoms in Patients with Nasal Septal Deviation and Patients with Chronic Rhinosinusitis

Introduction: Disorders of the nose and paranasal sinuses are among the most common chronic illnesses. Although considerable progress has been made in the medical and surgical control of these diseases, a large number of questions relating to the diagnosis, evaluation, and treatment of these conditions remain unanswered. The aim of the present study was to evaluate differences in the frequency ...

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Symptoms in chronic rhinosinusitis with and without nasal polyps.

OBJECTIVES/HYPOTHESIS In this study we analyzed differences in symptoms scored between chronic rhinosinusitis patients with (CRSwNP) and without nasal polyps (CRSsNP). According to the European Position Paper on Rhinosinusitis and Nasal Polyps, CRSwNP and CRSsNP diagnoses are defined by clinical criteria supported with endoscopy. We wanted to know if it is possible to make an accurate distincti...

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Symptoms of chronic rhinosinusitis with and without nasal polyps

Background According to EPOS, chronic rhinosinusitis with and without nasal polyps diagnoses are defined by clinical criteria, supported with endoscopy. We want to know if it is possible to make an accurate distinction between patients with and without nasal polyps based on a limited number of clinical criteria, collected by health-related quality of life questionnaires. A validated instrument ...

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The bacteriology of chronic rhinosinusitis with and without nasal polyps.

OBJECTIVE To compare the bacteriologic findings in ethmoidal biopsy specimens and nasal lavage samples from healthy control patients and from patients with chronic rhinosinusitis (CRS) with nasal polyps (CRSNP+) and without nasal polyps (CRSNP-). DESIGN Comparative microbiologic investigation. SETTING University hospital. PATIENTS The study included 31 CRSNP+ patients, 13 CRSNP- patients,...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Clinical Immunology

سال: 2016

ISSN: 1710-1492

DOI: 10.1186/s13223-016-0123-3